PRINT AND ELECTRONIC PUBLICATIONS

 

I.                  Refereed publications

 

1. Kuo L, and Yiannoutsos CT:  “Empirical Bayes Risk Evaluation With Type-II Censored Data”, Journal of Statistical Computation and Simulation, 48:195-206, 1994

 

2. Navia, BA, Dafni U, Simpson, D, Tucker T, Slasor P, McArthur JC, Yiannoutsos CT, Zaborski, L, and Lipton, SA: “A Phase I/II Trial of Nimodipine for the Treatment of Neurological Manifestations Associated with HIV Infection, Including AIDS Dementia Complex and Peripheral Neuropathy. Neurology, 1998; 51(1) 221-228

 

1. Hall CD, Dafni U, Simpson D, Clifford D, Wetherill P, Cohen B, McArthur JC, Hollander H, Yiannoutsos CT[1],Major E,Millar L, Timpone J: Failure of Cytosine Arabinoside Therapy of Human Immunodeficiency Virus-I Associated Progressive Multifocal Leucoencephalopathy. New England Journal of Medicine, 1998; 338:19, 1345-51. Get the NEJM citation.  See also comment by J.E. Greenlee.

 

2. Kieburtz K, Simpson D, Yiannoutsos C, Max MB, Hall CD, Ellis RJ, Marra CM, McKendall R, Singer E, Dal Pan GJ, Clifford DB , Tucker T, Cohen B and the ACTG 242 Protocol Team.  A randomized controlled trial of amitriptyline and mexiletine for painful neuropathy in HIV infection.  Neurology, 1998; 51(6) 1682-8.

 

3. Clifford DB, Yiannoutsos C, Glicksman M, Simpson DM, Singer EJ, Piliero PJ, Marra CM, Francis GS, McArthur JC, Tyler KL, Tselis AC, Hyslop NE.  HAART improves prognosis in HIV-associated progressive multifocal leukoencephalopathy.  Neurology 1999; 52:623-625. Get the article.

 

4. Chen, MH, Ibrahim, JG, and Yiannoutsos, C. Prior Elicitation, Variable Selection and Bayesian Computation for Logistic Regression Models, Journal of the Royal Statistical Society, Series B, 1999; 61(1) 223-242. Get the article.

 

5. Rostasy K, Monti L, Kneissl M, Yiannoutsos CT, Bell J, Hedreen JC, Navia BA.  HIV infection, iNOS expression and microglial activation: pathogenetic relationship to the AIDS dementia complex. Annals of Neurology, 1999; 46 207-216.

 

6. Yiannoutsos CT, Major EO, Curfman B, Jensen PN, Gravell M, Hou J, Clifford DB, Hall CD.  Relation of JC virus DNA in the CSF to survival in AIDS patients with biopsy-proven Progressive Multifocal Leukoencephalopathy.  Annals of Neurology, 1999; 45(6) 816-820.

 

7. Price RW, Yiannoutsos CT, Clifford DB, Zaborski L, Tselis A, Sidtis JJ, Cohen B, Hall CD, Erice A, and Henry K. Neurological outcomes in late-stage HIV-1 infection: adverse influence of neurological impairment on Survival and protective effect of antiviral therapy.  AIDS, 1999; 13: 1677-1686. Get the article.  

 

8. Post MJD, Yiannoutsos C, Simpson D, Booss J, Clifford DB, Cohen B, McArthur JC, Hall CD and the ACTG 243 team.  PML in AIDS: An MR/Neurological/Pathological correlation.  Are there any MR or neurological findings predictive of patient survival? 1999.  Am J Neuroradiol. 1999; 20:1896-1906.

 

9. McArthur, JC, Yiannoutsos C, Simpson, DM, Adornato BT, Singer EJ, Hollander H, Marra C,  Rubin M, Cohen BA, Tucker T, Navia BA, Schifitto G, Katzenstein D. Rask C, Zaborski L, Smith ME, Shriver S, Millar L, Clifford DB. A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection.  Neurology, 2000; 54: 1080-1088. Get the article.

 

10.  Fichtenbaum, CJ, Koletar S, Yiannoutsos CT, Holland F, Pottage J, Cohn S, Walawander AL, Frame P, Feinberg J, Saag M, Van der Horst C, Powderly WG, Refractory Mucosal Candidiasis in Advanced Human Immunodeficiency Virus Infection.  Journal of Infectious Diseases, 2000; 30: 749-756

 

11.  Hewitt RG, Yiannoutsos CT, Higgs ES, Carey JT, Geiseler PJ, Soave R, Rosenberg R, Vasquez GJ, Wheat LJ, Fass RJ, Antonijevic Z, Walawander AL, Flanigan TP, Bender JF.  Paromomycin for the treatment of cryptosporidiosis in patients with advanced HIV infection: a randomized, double-blind, placebo-controlled trial Journal of Infectious Diseases, 2000; 31(4): 1084-1092

 

12.     Rostasy K, Monti L, Yiannoutsos CT, Wu J, Bell J, Hedreen J Navia BA.TNF-a expression, NF-kb activation and apoptosis in the AIDS Dementia Complex. Journal of Neurovirology, 2000; 6(6): 537-543.

 

13.  Yiannoutsos CT, De Luca A.  Designs for clinical trials to test the efficacy of therapeutics in progressive multifocal leukoencephalopathy. Journal of Neurovirology, 2001; 7(4): 369-374.

 

14.  Schifitto G, Simpson D, Haidich AB, Yiannoutsos CT, McArthur JC, for the ACTG 291 Protocol Study Team.  Long-Term Treatment with Open Label Nerve Growth Factor for HIV-Associated Sensory Neuropathy.  Neurology, 2001; 57(7): 1313-1316. Get the article.

 

15.  Simpson D, Katzenstein D, Haidich AB, Yiannoutsos CT, Millington D, McArthur JC and the ACTG 291/860 protocol study teams. Plasma Carnitine in HIV-Associated Neuropathy. AIDS, 2001; 15(16): 2207-2208

 

16.      Simpson DM, Haidich AB, Schifitto G, Yiannoutsos CT, Geraci AP, McArthur JC, Katzenstein DA. Severity of HIV-associated Neuropathy is Associated with Plasma HIV-1 RNA Levels. AIDS, 2002; 16(3): 407-412. Get the article.

 

17.  Polydefkis M, Yiannoutsos CT, Shriver S, Simpson DM, Cohen BA, Adornato BT, Hollander H, Marra CM, Clifford DB and McArthur JC.  Intraepidermal nerve fiber density in HIV-associated sensory neuropathy. Neurology, 2002; 58(1): 115-119. Get the article.

 

18.  Lee PL, Yiannoutsos CT, Ernst T, Chang L, Marra CM, Jarvik JG, Richards TL, Kwok EW, Kolson DL, Simpson D, Tang CY, Schifitto G, Ketonen LM, Meyerhoff DJ, Lenkinski RE, Gonzalez RG, Navia BA. MRS study of the AIDS dementia complex: Validation and preliminary analysis.  J Magn Reson Imaging. 2003; 17(6):625-33. Get the article.

 

19.  Smith, KM, Daly M, Bauer L, Fischer M, Yiannoutsos CT, Bauer L, Barkley R, Navia BA.  Association of the Dopamine Beta Hydroxylase gene with Attention Deficit Hyperactivity Disorder: Genetic Analysis of the Milwaukee Longitudinal Study.  Am J Med Genet. 2003; 119B(1):77-85

 

20.  Rostasy K, Egles C, Chauhan A, Kneissl M, Bahrani P, Yiannoutsos C, Hunter DD, Nath A, Hedreen JC, Navia BA. SDF-1α is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study.  J Neuropathol Exp Neurol. 2003; 62(6):617-26. Get the article.

 

21.  Wiesenauer CA Schmidt CM, Cummings OW, Yiannoutsos CT, Howard TJ,  Wiebke EA, Goulet RJ, McHenry L, Sherman S, Lehman GA, Cramer H, Madura JA.  Preoperative predictors of malignancy in pancreatic intraductal papillary mucinous neoplasms. Arch Surg; 2003;138:610-618

 

22.  Nakas C, Yiannoutsos CT, Bosch RJ, Moyssiadis C.  Assessment of diagnostic markers by goodness-of-fit tests. Statist Med; 2003; 22(15): 2503-2513. Get the article.

 

23.  Vaena DA, Walker P, Pennington K, Stephens A, Stender MJ, Yiannoutsos CT, Young C, Stoner C, Cripe LD.  Phase II study of low-dose topotecan in myelodysplastic syndromes: a Hoosier Oncology Group (HOG) study.  Leuk Res; 2004; 28(1):49-52.

 

24.  Schneider BP, Kesler KA, Brooks JA, Yiannoutsos CT and Einhorn LH.  Outcome of patients with residual germ cell or non-germ cell malignancy after resection of primary mediastinal non-seminomatous germ cell cancer.  J Clin Oncol. 2004;22(7):1195-200

 

25.  Goldman M, Zackin R, Fichtenbaum CJ, Skiest DJ, Koletar SL, Hafner R, Wheat LJ, Nyangweso PM, Yiannoutsos CT, Schnizlein-Bick CT, Owens S, Aberg JA; AIDS Clinical Trials Group A5038 Study Group.  Safety of discontinuation of maintenance therapy for disseminated histoplasmosis after immunologic response to antiretroviral therapy.  Clin Infect Dis. 2004; 38(10):1485-1489

 

26.  Schmidt CM, Powell ES, Yiannoutsos CT, Howard TJ, Wiebke EA, Wiesenauer CA, Baumgardner JA, Cummings OW, Lillemoe KD, Jacobson L, Broadie TA, Goulet RJ, Curie EA, Cardenes H, Watkins JM, Loehrer PJ and Madura JA.  Pancreaticoduodenectomy: A twenty year experience in 516 patients. Arch Surgery 2004; 139: 718-727.

 

27.  Nakas CT, Yiannoutsos CT.  Ordered multiple class ROC analysis with continuous measurements.  Statist Med 2004; 23: 3437-3449. Get the article.

 

28.  Yiannoutsos CT, Ernst T, Chang L, Lee PL, Richards T, Marra C, Meyerhoff DJ, Jarvic J, Kolson D, Schifitto G, Ellis RJ, Swindells, Simpson DM, Miller EN, Gonzalez RG, Navia BA.  Patterns of regional brain metabolism and diagnostic utility of proton MRS in AIDS Dementia Complex.  Neuroimage 2004; 23(3): 928:935. Get the article.

 

29.  Chang L, Lee PL, Yiannoutsos CT, Ernst T, Marra CM, Schifitto G,  Miller EN, Jarvik J, Kolson D,  Gonzalez RG, Navia BA.  A Multicenter in-vivo proton MRS study of HIV-associated brain injury.  Neuroimage 2004; 231336-1347. Get the article.

 

30.  Villella AD, Yao J, Getty RR Juliar BE, Yiannoutsos CT, Hartwell JR, Cai S, Sadat MA, Cornetta K, Williams DA, Pollok KE.  Real-Time PCR: An effective tool for measuring transduction efficiency in human hematopoietic progenitor cells. Mol Ther, 2005; 11(3):483-491.

 

31.  Li J, Juliar BE, Yiannoutsos CT,  Ansari R, Fox E, Fisch MJ, Einhorn LH, Sweeney CJ. Weekly paclitaxel and gemcitabine in advanced transitional cell carcinoma of the urothelium: A Phase II Hoosier Oncology Group study. J Clin Onc, 2005; 23(6): 1185-1191. Get the article.

 

32.  Li L, Shi H, Yiannoutsos CT, Huang T-H-M, Nephew KP.  Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system.  J Comp Biol, 2005; 12(3):270-390. Get the article.

 

33.  Srour EF, Tong X, Sung KW, Plett PA, Rice S, Daggy J, Yiannoutsos CT, Abonour R, Orschell CM.   Cytokine modulation of proliferation kinetics and primitive hematopoietic potential on individual CD34+CD38-/Io cells in G0 during successive in vitro cell divisions.  Blood, 2005; 105(8):3109-16

 

34.  Fakiris AJ, Cardenes HR, Moore DH, Reddy SR, Look KY, Yiannoutsos CT, Randall ME.  Intraperitoneal radioactive phosphorus ( 32P ) and vaginal brachytherapy as adjuvant treatment for uterine papillary serous carcinoma and clear cell carcinoma: A Phase II Hoosier Oncology Group (97-1) study.   Gyn Onc, 2005; 96(3):818-823. Get the article.

 

35.  Rostasy K, Gorgun G, Kleyner Y, Garcia A, Kramer M, Melanson SM, Mathys J-M, Yiannoutsos CT, Skolnik PR, Navia BA. TNF-a leads to increased cell surface expression of CXCR4 in SK-N-MC cells. J Neurovirol 2005; 11(3):247-55.

 

36.  Sweeney C, Liu G, Yiannoutsos CT, Kolesar J, Horvath D, Staab MJ, Fife K, Armstrong V, Treston A, Sidor C, Wilding G. A Phase II multicenter, randomized, double-blind, safety, PK, PD, and efficacy study of oral 2-methoxyestradiol in hormone refractory prostate cancer. Clin Cancer Res, 2005; 11(18): 6625-6633. Get the article. See more details of the changepoint model.

 

37.  Ellis RJ, Evans SR, Clifford DB, Moo L, McArthur JC, Collier AC, Benson C, Bosch R, Simpson D, Yiannoutsos CT, Yang Y, Robertson K; Neurological AIDS Research Consortium; AIDS Clinical Trials Group Study Teams A5001 and A362. J Neurovirol, 2005; 11(6):503-11.

 

38.     Wools-Kaloustian K, Kimaiyo S, Diero L, Siika AM, Sidle J, Yiannoutsos CT, Musick BS, Einterz RM, Fife KH, Tierney, WM The clinical and immunologic outcomes of an antiretroviral treatment program in western Kenya: retrospective cohort study. AIDS, 2006; 20:41-48. Get the article.

 

39.     Kurup A, Murry DJ, Dobrolecki L, Estes D, Yiannoutsos CT, Mariano L, Sidor C, Hickey R, Hanna N.  Recombinant human angiostatin (rhAngiostatin) in combination with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer: a phase II study from Indiana University. Ann Oncol, 2006; 17:97-103. Get the article.

 

40.     Wruck LM, Yiannoutsos CT, Hughes, MD.   A sequential design to estimate sensitivity and specificity of a diagnostic test. Stat Med, 2006; 25:3458-3473. Get the article.

 

41.     Matei D, Emerson RE, Lai YC, Baldridge LA, Rao J, Yiannoutsos C, Donner DD. Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer. Oncogene, 2006; 25:2060-2069. Get the article.

 

42.     Paul R, Yiannoutsos CT, Miller EN, Singer E, Lee, P-L, Chang L, Marra CM, Schifitto G, Ernst T, Richards T, Jarvik J, Price R, Meyerhoff DJ, Kolson D, Ellis RJ, Gonzalez RG, Lenkinski R, Cohen RA, Navia BA.  Proton Proton MRS and Neuropsychological Correlates in AIDS Dementia Complex: Evidence of Subcortical Specificity. Accepted J Neuropsych Clin Neurosciences.

 

43.     Schifitto G, Yiannoutsos CT, Simpson D, Navia BA. A Placebo-controlled study of memantine for the treatment of HIV-associated sensory neuropathy. J Neurovirol, 2006; 12:328-331

 

44.     Nyandiko WM, Ayaya S, Nabakwe E, Tenge C, Sidle JE, Yiannoutsos CT, Musick BS, Kigotho E, Wools-Kaloustian K, Tierney WM.  Outcomes of HIV-infected children on anti-retroviral therapy at AMPATH HIV clinics in Western Kenya. JAIDS, 2006; 43:418-425. Get the article.

 

45.     Timmerman R, McGarry R, Yiannoutsos C, Papiez L, Tudor K, DeLuca J, Ewing M, Abdulrahman R, DesRosiers C, Williams M, Fletcher J. Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer. J Clin Oncol, 2006;24:4833-4839.  Get the article.

 

46.     Suvannasankha A, Fausel C, Juliar BE, Yiannoutsos CT, FisherWB, Ansari RH, Wood LL, Smith GG, Cripe LD, Abonour R.  Final report of Toxicity and Efficacy of a Phase II Study of Oral Cyclophosphamide, Thalidomide, and Prednisone (CTP) for Patients with Relapsed or Refractory Multiple Myeloma: A Hoosier Oncology Group Trial: HEM01-21. Oncologist, 2007; 12:99-106. Get the article.

 

47.     Odero, W, Rotich, J, Yiannoutsos, CT, Ouna T, Tierney WM. Innovative approaches to application of information technology in disease injury surveillance and prevention in Western Kenya. J Biomed Inform, 2007.  Get the article.

 

48.     Navia, BA, Yiannoutsos CT, Schifitto G, Marra CM, Jarvik J, Chang L, Ernst T, Miller EN, Singer E, Ellis RJ, Kolson, DL, Simpson D, Nath A, Berger  J, Shriver S, Millar L, Colquhoun D,  Lee P-L, Lekinski R, Gonzalez RG, Lipton SA.  A phase II trial of memantine for HIV-associated cognitive impairment: A neuropsychological and proton MRS study. AIDS, 2007; In press.

 

49.     Yip-Schneider MT, Wu H, Ralstin M, Yiannoutsos C, Crooks PA, Neelakantan S, Noble S, Nakshatri H, Sweeney CJ, Schmidt CM.  Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo. Mol Can Therapeutics, 2007; 6:1736-44. Get the article.

 

50.     Yiannoutsos CT, Nakas CT, Navia BA. Assessing multiple-group diagnostic problems with multi-dimensional receiver operating characteristic surfaces: Application to HIV-related neurological injury. Neuroimage, 2007; Accepted.

 

51.     Schmidt CM, Choi J, Powell ES, Yiannoutsos CT, Howard TJ, Zyromski NJ,  Nakeeb A, Pitt HA, Wiebke EA, Madura JA, Lillemoe KD. Pancreatic Fistula Following Pancreaticoduodenectomy: Clinical Predictors and Patient Outcomes. Under revision J Gastrointest Surg.

 

 

I.            Non-refereed publications

 

52.     Yiannoutsos CT, and Gelfand, AE:  “Simulation Approaches for Calculations in Directed Graphical Models”.  Technical Report, 21, 1991

 

53.     Yiannoutsos CT, and Gelfand AE:  “Subgraph Approximations for Large Directed Graph Models”, Statistical Decision Theory and Related Topics, V., 441-452, 1994

 

54.     Hall CD, Yiannoutsos C, Clifford D. Progressive multifocal leukoencephalopathy, HIV, and highly active antiretroviral therapy. Letter. New England Journal of Medicine, 1998;339:849.

 

55.     Miller LC, Yiannoutsos CT and Hughes MD.  Diagnostic test validation: Optimal designs.  Proceedings of the 17th International Workshop in Statistical Modeling, Chania, Greece.  Stasinopoulos D, Touloumi G editors; 2002; 463-469.

 

56.     Nakas CT, Yiannoutsos CT.  Ordered Multiple Class ROC Analysis. In the Encyclopedia of Biopharmaceutical Statistics, Shein-Chung Chow editor; Decker Encyclopedias. 2006; In press.  Get the article.

 

II.  Manuscripts in preparation

 

57.     Nakas CT, Yiannoutsos CT, Li L, Kagaris D.  ROC-based indices for class discovery and prediction in DNA microarray data. Submitted.

 

58.     Yu M, Yiannoutsos CT.  Bivariate sequential design for Phase II trials with trade-off.  Submitted.

 

59.     Letendre S, Zheng J, Kaul M, Lopez A, Yiannoutsos CT, Ellis RJ, Taylor M, Marquie-Beck J, Zimmerman J, Lipton S, Gendelman H, Navia BA and the ACTG 301 and 700 Teams. Chemokines in cerebrospinal fluid correlate with patterns of cerebral injury as measured by magnetic resonance spectroscopy.

 

60.     Kimaiyo S, Diero L, Siika A, Ying J, Yiannoutsos CT, Cohen J, Mamlin J, Einterz B, Carter J. Absolute lymphocyte count (ALC) as a predictor of CD4 count in Moi Teaching and Referral Hospital, Eldoret, Kenya.

 

61.     David F. Tate, DF, Brickman AM, Paul, RH, Cohen RA, Flanigan T,  Ernst T, Bramley K, Yiannoutsos CT, Navia BA for the ACTG 700 Team and HIV MRS Consortium. Gross and Regional Morphometry of Corpus Callosal Area and Cognition in HIV-Infected Patients. Submitted

 

62.     Nikoloulopoulos AK, Yiannoutsos CT. A Meta-analysis of short-term effects of air pollution on asthma. Submitted.

 

63.     Sinclair E, Ronquillo R, Lollo N, Yiannoutsos CT, Deeks SG, Spudich S, Price RW. T Lymphocyte Activation and Cerebrospinal Fluid HIV Treatment Effects. . . . Submitted.

 

64.     Hoopes D, Fletcher J, Lin P-F, Tann M, Yiannoutsos CT, Henderson M,  Williams M, McGarry R, Timmerman R. A Prospective Trial of Serial FGD-PET in Patients with Medically Inoperable Stage I Non-Small Cell Lung Cancer Treated with Hypofractionated Stereotactic Body Radiotherapy (SBRT). Submitted JNM.

 

65.     Henderson M, McGarry R, Yiannoutsos CT, Fakiris A, Hoopes D, Williams M, Timmerman R. Baseline pulmonary function as a predictor for survival and decline in pulmonary Function over time in patients undergoing stereotactic body radiotherapy for the treatment of stage I non-small cell lung cancer. Submitted Chest.

 

66.     Yang F-C, Ingram DA, Chen S, Li X, Morgan T, Yuan J, Yiannoutsos C, Yu M, Zhang S, Vakili ST, Hutchins G, Parada L, Clapp DW. Adoptive transfer of Nf1+/-  bone marrow is sufficient for neurofibroma progression in genetically engineered mice. Submitted.

 


[1] The name is misspelled in the publication (“Yainnoutsos”)