|
|
Syllabus: Short course: Biostatistics for Health Care Providers
SUGGESTED INSTRUCTIONAL BOOK
Participants are encouraged to bring to the course a copy of the book:
Basic and Clinical Biostatistics, 4th edition, © 2004, by Dawson-Saunders and Trapp, ISBN# 0071410171.
The book will be available
for $55.00 plus tax at:
IUPUI Medical and Law Bookstore
Student Union Building
620
Union Drive
Indianapolis, IN 46202
The bookstore phone number is (317) 274-7167
| Session I |
| |
Study Design - Types of study designs with emphasis on observational studies |
| |
Hypothesis Testing & Confidence Interval Estimation - Hypothesis test, type I and type II errors, statistical significance vs. practical significance,
confidence interval, sample size estimation |
| |
Comparisons of Means - Paired T-test, group T-test, Wilcoxon, Mann Whitney, one-way ANOVA, multiple
comparisons, non-parametric ANOVA, sample size estimation
|
| |
Analysis of Categorical Data -
Estimation and testing of single proportions, two proportions, tests of association |
| Session II |
| |
Evaluation of Diagnostic Tests -
Sensitivity, specificity, ROC curves, measures of agreement |
| |
Issues in Clinical Trials -
Design, analysis, interim reviews, ethics, and reporting of clinical trials |
| |
Correlation and Simple Linear Regression -
Correlation (Spearman & Pearson), regression, prediction, model evaluation
|
| |
Basics of Data Management -
Database design, form design, data entry |
| Session III |
| |
Multiple Linear & Logistic Regression -
Interpretation of coefficients, R2, odds ratios, logistic regression |
| |
Analysis of Longitudinal Studies -
Introduction, examples, efficiency and sample size, analysis, missing values |
| |
Survival Analysis -
Censoring vs. failure, Kaplan-Meier curves, log-rank test, proportional hazards model
|
| |
Design of Genetic Studies -
Review of basic genetics, study designs for gene searching, linkage and association
methods based on modern molecular laboratory techniques
|
|