G652: Biostatistics I
Division of Biostatistics
Fall 2007
Textbook
Principles
of Biostatistics, 2nd Edition, by Pagano and Gauvreau
Prerequisite
G651
or equivalent to G651
Syllabus
Multiple
linear regression:
Multiple correlation coefficient and interpretations,
Inference, Confounder bias,Polynomial terms, Indicator variables, Interactions, Model
selection, Residual plots, Outliers, Examining the assumptions, Transformation
of predictors, Common misuse of regression models
Analysis
of Variance (ANOVA):
Review of One factor ANOVA and, Multiple comparisons, Multi-factor
ANOVA, Interactions
Analysis
of Covariance (ANCOVA):
Indicator variables, Interactions
Random
effect models and analysis of repeated measures
Logistic
regression:
2x2 tables and odds ratio, Parameter estimation and
inference
Diagnostic
Tests:
Sensitivity and Specificity, ROC curve
Survival
analysis:
Censoring, Survival function, Hazard function, Estimation
of survival function and
Hazard function (life-table method and Kaplan-Meier
method), Comparing survival
functions, Cox’s Proportional hazard model
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